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Theoretical and Computational Biophysics - Einzelansicht

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Veranstaltungsart Vorlesung Kurztext A 143
Veranstaltungsnummer 340232 SWS 2.00
Semester WiSe 2021/22 Studienjahr
Erwartete Teilnehmer/-innen 30 Hyperlink
Turnus keine Übernahme
Credits 2
Sprache englisch
Termine :
  Tag Zeit Turnus Termin Raum Lehrperson Status Bemerkung fällt aus am Max. Teilnehmer/-innen Module
Einzeltermine anzeigen Mo. 16:00 bis 17:30 wöch. 25.10.2021  bis

Zugeordnete Personen
Zugeordnete Personen Zuständigkeit
de Groot, Bert L., apl. Prof. Dr.
Grubmüller, Karl Helmut, Hon.-Prof. Dr.
Zuordnung zu Einrichtungen
Göttinger Graduiertenschule für Neurowissenschaften, Biophysik und molekulare Biowissenschaften (GGNB)
Georg-August University School of Science (GAUSS) (für Mathematik und Naturwissenschaften)

The course will alternate between two rooms in the Physics Faculty: Lectures take place in a lecture hall and the hands-on computer tutorial takes place in a computer/seminar room, Friedrich-Hund-Platz 1, 37077 Göttingen. The room numbers will be announced in due time. An account to access the CIP-Pool Computers of the Physics Faculty is required: Please contact the administrator in advance.


Basic knowledge in physics is preferred, programing skills are not required. For interested students the subsequent lecture " Biomolecular Physics and Simulations" is recommended in the following semester.


This combined lecture and hands-on computer tutorial focuses on the basics of computational biophysics and deals with questions like "How can the particle dynamics of thousands of atoms be described precisely?" or "How does a sequence alignment algorithm work?" No cell could live without the highly specialized macromolecules. Proteins enable virtually all tasks in our bodies, e.g. photosynthesis, motion, signal transmission and information processing, transport, sensor system, and detection. The perfection of proteins had already been highly developed two billion years ago.

The aim of the lecture is to develop a physical understanding of those "nano maschines" by using modern concepts of non-equilibrium thermodynamics and computer simulations on the dynamics on an atomic scale. Moreover, the lecture shows (by means of examples from current research) how computers can be used in modern biophysics, e.g. to simulate the dynamics of biomolecular systems, molecular charge transfer or to calculate or refine a protein structure.

During the exercises, the knowledge presented in the lecture is to practical examples to further deepen and strengthen the understanding. By completing homework sets, which are distributed after each lecture, additional aspects of the addressed topics during the lecture shall be worked out. The homework sets are collected during the corresponding exercises.


Target group: GGNB and GAUSS doctoral students.


Die Veranstaltung wurde 1 mal im Vorlesungsverzeichnis WiSe 2021/22 gefunden: